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Remote Per Diem Clinical Research Nurse jobs

51 open positions in the United States, newest first.

Per diem clinical research nurses are registered nurses who work on clinical trials on an as-needed basis rather than a fixed schedule. They are responsible for participant safety and for carrying out study procedures exactly as the protocol specifies, then documenting them accurately. Per diem means shifts are picked up as studies require, usually without guaranteed hours.

About the Per Diem Clinical Research Nurse role

What the work looks like

  • Screen potential participants against the protocol's inclusion and exclusion criteria and walk them through informed consent.
  • Conduct study visits by phone or video, assessing symptoms, reviewing medications and recording adverse events.
  • Enter visit data into the electronic data capture system and resolve queries raised by study monitors.
  • Report serious adverse events to the investigator and sponsor within the timelines the protocol requires.
  • Coordinate with investigators, study coordinators and home health or lab vendors to keep visits on schedule.

What employers ask for

  • Active registered nurse (RN) license
  • Good Clinical Practice (GCP) training
  • Clinical experience in a relevant specialty
  • Electronic data capture and eSource systems
  • Informed consent and adverse event reporting
  • Research certification such as CCRP or CCRC

Doing this job remotely

Remote research nursing has grown with decentralized trials, where visits happen by telehealth or in the participant's home. Nurses generally need a license valid in the state where the participant is located, so multistate or compact licensure matters. Some roles still involve home visits or site days, and per diem scheduling can mean evenings and uneven hours.

Where it comes from and where it leads

Most come from bedside or clinic nursing, often in oncology, cardiology or another specialty with active trials. Per diem work can lead to a staff clinical research nurse position, then to research nurse coordinator, clinical research associate or clinical trial manager.